男，汉族，1991年01月生，山东淄博人，博士，讲师。
通讯地址：盐城市希望大道南路2号盐城师范学院海洋与生物工程学院，邮编：224051。
E-mail：zhaipf@yctu.edu.cn
1.学习经历
2014.9-2019.9，南京师范大学，生命科学学院，微生物学，博士（硕博连读）；
2012.9-2014.6，临沂大学，生命科学学院，生物科学，本科。
2.工作经历
2023.11至今，盐城师范学院，海洋与生物工程学院，讲师；
2019.9-2023.1，南京师范大学，生命科学学院，博士后；
3.承担的教学任务
主讲微生物学、分子生物学、微生物学实验等课程。
4.主要研究方向
病原真菌基因功能解析，烟曲霉耐药及致病分子机制，微生物资源开发利用。
5.主要科研成果
（1）主持或参加的科研项目
1.国家自然科学基金面上项目，82172292，烟曲霉钙调磷酸酶参与的液泡（Vacuole）钙信号调控网络作为新型抗真菌药物靶点的探索，2022.01-2025.12，第二参与人。
2.中德国际合作与交流项目，31861133014，钙信号与光感知途径在曲霉逆境响应和极性生长中的信号交流，2019-2021，参与。
3.国家自然科学基金面上项目，31770086，烟曲霉Cys(6)Zn(2)型转录因子 LeuB 家族调控亮氨酸合成网络和毒力的解析，2018-2021，参与。
4.江苏省高校优秀科技创新团队项目，17CXTD00014，微生物功能基因的挖掘和资源利用，2018-2021，参与。
（2）近年来发表的论文
1. Pengfei zhai, Yinyan Ma, Wenlong Du, Ling Lu*. The metal chaperone protein MtmA plays important roles in antifungal drug susceptibility in Aspergillus fumigatus. Friontier in Microbiology. 2022 Dec 02. doi: 10.3389/fmicb.2022.1062282
2. Pengfei Zhai, Landan Shi, Guowei Zhong, Jihong Jiang, Jingwen Zhou, Xin Chen, Guokai Dong, Lei Zhang, Rongpeng Li*,Jinxing Song*. The OxrA Protein of Aspergillus fumigatus Is Required for the Oxidative Stress Response and Fungal Pathogenesis. Applied and Environmental Microbiology. 2021 Oct 28;87(22):e0112021.
3. Pengfei Zhai, Yinyan Ma, Huan Xu, Ling Lu*. Molecular Characterization and the Essential Biological Function of the Metal Chaperone Protein MtmA in Aspergillus fumigatus. Applied and Environmental Microbiology. 2022 May 10;88(9):e0018222.
4. Pengfei Zhai, Wenlong Du, Nanbiao Long*, Ling Lu*. A GATA-type transcription factor SreA affects manganese susceptibility by regulating the expression of iron uptake related genes. Fungal Genetics and Biology. 2022 Sep 7;163:103731.
5. Pengfei Zhai, Jinxing Song, Lu Gao and Ling Lu*. A sphingolipid synthesis-related protein OrmA in Aspergillus fumigatus is responsible for azole susceptibility and virulence. Cellular Microbiology. 2019 Dec;21(12):e13092.
6. Pengfei zhai, Yanfei Chai, Ling Lu*. Fungal zinc homeostasis and its potential as an antifungal target: a focus on the human pathogen Aspergillus fumigatus. Microorrganisms. 2022 Dec 14.
7. Wenlong Du, Pengfei Zhai, Tingli Wang, Michael J. Bromley, Yuanwei Zhang*, Ling Lu*. The C2H2 Transcription Factor SltA Contributes to Azole Resistance by Coregulating the Expression of the Drug Target Erg11A and the Drug Efflux Pump Mdr1 in Aspergillus fumigatus. Antimicrobial Agents and Chemotherapy. 2021.
8. Wenlong Du, Pengfei Zhai, Shuai Liu, Yuanwei Zhang*, Ling Lu*. The Copper Chaperone CcsA,
Coupled with Superoxide Dismutase SodA, Mediates the Oxidative Stress Response in Aspergillus
fumigatus.Applied and Environmental Microbiology. 2021.
9. Jinxing Song, Pengfei Zhai, Ling Lu*. Damage resistance protein (Dap) contributes to azole resistance in a sterol-regulatory-element-binding protein SrbA-dependent way. Applied Microbiology and Biotechnology. 2016.
10. Jinxing Song, Xiao Liu, Pengfei Zhai , Jingjing Huang, Ling Lu*. A putative mitochondrial calcium uniporter in A. fumigatus contributes to mitochondrial Ca 2+ homeostasis and stress responses. Fungal Genetics and Biology. 2016.
11. Jinxing Song, Pengfei Zhai, Yuanwei Zhang, Caiyun Zhang, Hong Sang, Guanzhu Han, Nancy P. Keller, Ling Lu*. The Aspergillus fumigatus Damage Resistance Protein Family Coordinately Regulates Ergosterol Biosynthesis and Azole Susceptibility. mBio. 2016.
（3）近年来获得的科研奖励
1.南京市第十二届自然科学优秀学术论文奖三等奖（2018年，2/4）；
2.徐州市自然科学优秀学术论文一等奖（2022年,2/3）。